Monday, June 11, 2012

Weekly Article: CTs, Cancer, Lancet, the News



This week, I highlight a recent article in the Lancet on CT scans and subsequent risk of cancer. This retrospective cohort study used the UK’s NHS database and parsed out patients getting a CT and estimated radiation dosages based on when they obtained the CT. The data showed a positive correlation between radiation exposure and risk of subsequent cancer. The relative risk between low-dose and high-dose was 3.18 for leukemia and 2.8 for brain tumors, while absolute risk is about one excess case of leukemia and brain tumor may result per 10,000 CT scans.
I bring this up not because we don’t already suspect that more CT leads to higher malignancy risk but because it made a lot of major news outlets. Depending on how parents interpret the findings, they may be more likely to hesitate and it’s important to know where they’re coming from and highlights the usefulness of using our head trauma decision tool.
It's also a nice example of interpreting absolute and relative risks in uncommon events. As an example, here are two headlines from Fox News about the same article, posted 20 hours apart.

“Childhood CT scans can triple the risk of brain cancer”!!! (exclamation points are my addition)

Link to Abstract


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